什么是皮肤屏障?
What is a skin barrier?
皮肤是人体最大的器官,扮演机体“防弹衣”的角色,帮助机体避免外界细菌、尘埃、刺激等的入侵,也保护身体内的物质流失。皮肤最外层叫角质层,角质层由15-20层扁平的角质细胞构成,并且细胞间充满着各种脂质成分,角质层这种结构被称为“砖墙结构”,可以抵御外界各种物理、化学和生物性有害因素对皮肤的侵袭,还能防止内源性物质包括水在内的分子自表皮丢失。皮肤屏障功能不完整或被破坏时,其对外用化学物质吸收增加,神经末梢受到的保护较少,经皮水丢失(TEWL)增加,是皮肤敏感的原因之一,容易引起脂溢性皮炎、玫瑰痤疮、酒渣鼻、颜面部再发性皮炎、面部湿疹等等。
The skin is the largest organ of the human body, playing the role of the body's "bulletproof vest", helping the body avoidInvasion of bacteria, dust, irritation, etc. from the outside also protects the body from material loss. Skin mostThe outer layer is called the stratum corneum. The stratum corneum consists of 15-20 layers of flat keratinocytes, and the cellsFilled with various lipid components, this structure of the stratum corneum is called the "brick wall structure" and canResist the invasion of various physical, chemical and biological harmful factors to the skin from outside, and preventEndogenous substances, including water, are lost from the epidermis. The skin barrier function is incomplete or When destroyed, its absorption of external chemicals increases, and the nerve endings are less protected.Increased transcutaneous water loss (TEWL) is one of the causes of skin sensitivity, which is easy to cause seborrhea Dermatitis, rosacea, rosacea, recurrent facial dermatitis, facial eczema, etc.